Heat oven to 200 degrees. Prepare a 12 cup muffin tin by spraying 8 of the muffin cups with cooking spray. In a large skillet, cook beef over medium-high heat until no longer pink; drain. Stir in the ketchup, brown sugar, mayo mustard sauce. Let cook for a couple of minutes and then remove from the heat; set aside.

Flatten out one biscuit and press onto the bottom and up the sides of a muffin cup. Repeat with remaining biscuits. Spoon beef mixture into cups. Top each with some cheese cubes. Bake for 12-14 minutes or until golden brown on edges and puffed up. Let cool for about 5-10 minutes in the pan and then serve.